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Mary J C Hendrix Selected Research

SERPIN-B5 (maspin)

1/2021Editor's Note: The Paradoxical Expression of Maspin in Ovarian Carcinoma.
1/2017An Essential Role of Maspin in Embryogenesis and Tumor Suppression-Response.
10/2014Internalization by multiple endocytic pathways and lysosomal processing impact maspin-based therapeutics.
12/2012Maspin: molecular mechanisms and therapeutic implications.
6/2009Temporal and spatial expression patterns for the tumor suppressor Maspin and its binding partner interferon regulatory factor 6 during breast development.
9/2008IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells.
7/2008IRF6 in development and disease: a mediator of quiescence and differentiation.
4/2008Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner.
4/2007Elucidating the function of secreted maspin: inhibiting cathepsin D-mediated matrix degradation.
12/2006Biological functions of maspin.
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Mary J C Hendrix Research Topics

Disease

72Neoplasms (Cancer)
12/2020 - 02/2002
34Melanoma (Melanoma, Malignant)
01/2019 - 10/2002
25Breast Neoplasms (Breast Cancer)
03/2019 - 07/2002
7Carcinoma (Carcinomatosis)
01/2021 - 09/2002
6Neoplasm Metastasis (Metastasis)
01/2019 - 07/2002
6Ovarian Neoplasms (Ovarian Cancer)
05/2013 - 09/2002
5Hypoxia (Hypoxemia)
03/2016 - 04/2005
4Disease Progression
01/2019 - 01/2010
4Prostatic Neoplasms (Prostate Cancer)
08/2011 - 02/2002
3Carcinogenesis
12/2020 - 12/2009
2Primitive Neuroectodermal Tumors (PNET)
03/2018 - 01/2015
2Triple Negative Breast Neoplasms
01/2016 - 12/2014
2Lewis Lung Carcinoma
01/2014 - 01/2012
2Chondrosarcoma
09/2010 - 12/2009
2Ovarian Epithelial Carcinoma
04/2004 - 10/2002
2Ascites
10/2002 - 09/2002
1Starvation
12/2020
1Polyps
12/2020
1Nevus (Nevi)
08/2016
1Dysplastic Nevus Syndrome (Dysplastic Nevus)
03/2016
1Inflammation (Inflammations)
01/2015
1Wounds and Injuries (Trauma)
01/2015
1Atherosclerosis
07/2014
1Glioblastoma (Glioblastoma Multiforme)
12/2013

Drug/Important Bio-Agent (IBA)

26Proteins (Proteins, Gene)FDA Link
03/2018 - 07/2002
18SERPIN-B5 (maspin)IBA
01/2021 - 07/2002
10Biological ProductsIBA
03/2015 - 10/2002
8PlasticsIBA
03/2016 - 12/2005
7Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
10/2014 - 05/2003
5Biomarkers (Surrogate Marker)IBA
08/2016 - 01/2010
5cadherin 5IBA
05/2012 - 05/2003
5CollagenIBA
04/2007 - 08/2002
5SerpinsIBA
12/2006 - 09/2002
5Focal Adhesion Protein-Tyrosine KinasesIBA
03/2006 - 12/2002
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2016 - 05/2012
4Transforming Growth Factor beta (TGF-beta)IBA
03/2016 - 04/2007
4Conditioned Culture MediaIBA
03/2016 - 08/2002
4LigandsIBA
03/2015 - 06/2010
4Messenger RNA (mRNA)IBA
03/2015 - 08/2002
4Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
04/2008 - 08/2002
4Matrix Metalloproteinases (MMPs)IBA
04/2004 - 11/2002
3Androgen Receptors (Androgen Receptor)IBA
08/2011 - 09/2002
3Oxygen (Dioxygen)IBA
04/2008 - 12/2005
3Tyrosine (L-Tyrosine)FDA Link
03/2006 - 07/2002
3KalininIBA
08/2003 - 11/2002
2DNA (Deoxyribonucleic Acid)IBA
03/2018 - 12/2009
2Free RadicalsIBA
03/2016 - 05/2003
2Angiogenesis InhibitorsIBA
03/2016 - 10/2004
2Estrogen ReceptorsIBA
01/2016 - 04/2008
2Pharmaceutical PreparationsIBA
01/2015 - 04/2014
2MicroRNAs (MicroRNA)IBA
11/2010 - 12/2009
2Phosphotransferases (Kinase)IBA
06/2010 - 03/2006
2Cathepsin DIBA
01/2010 - 04/2007
2EnzymesIBA
01/2010 - 08/2002
2Interferon Regulatory FactorsIBA
06/2009 - 07/2008
2Notch ReceptorsIBA
06/2008 - 11/2005
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
04/2008 - 12/2005
2AminopropionitrileIBA
04/2008 - 12/2005
2Collagen Type I (Type I Collagen)IBA
03/2006 - 04/2004
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
11/2005 - 08/2004
2FAK-related nonkinaseIBA
11/2005 - 10/2004
2Cadherins (E-Cadherin)IBA
10/2005 - 03/2004
2OligonucleotidesIBA
07/2005 - 08/2002
2AndrogensIBA
01/2005 - 09/2002
2Metalloproteases (Metalloproteinases)IBA
04/2004 - 08/2003
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
08/2003 - 11/2002
2Laminin (Merosin)IBA
08/2002 - 02/2002
1Adenosine Triphosphate (ATP)IBA
12/2020
1PolymersIBA
12/2020
1PolyphosphatesIBA
12/2020
1Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA
12/2020
1Phosphates (Orthophosphate)IBA
12/2020
1Tumor Suppressor Protein p53IBA
03/2018
1RNA (Ribonucleic Acid)IBA
03/2018
1Acetylcysteine (Siran)FDA LinkGeneric
03/2016
1AntioxidantsIBA
03/2016
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2016
1Glutathione (Reduced Glutathione)IBA
03/2016
1Melanins (Melanin)IBA
03/2016
1Progesterone Receptors (Progesterone Receptor)IBA
01/2016
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2016
1human ERBB2 proteinIBA
01/2016
1Monoclonal AntibodiesIBA
10/2015
1dabrafenibIBA
10/2015
1Immunoglobulin G (IgG)IBA
10/2015
1Dacarbazine (DIC)FDA LinkGeneric
04/2015
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
03/2015
1Neutralizing AntibodiesIBA
03/2015
1Activin Receptors (Activin Receptor)IBA
03/2015
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2014
1Coloring Agents (Dyes)IBA
10/2014
1Small Interfering RNA (siRNA)IBA
05/2013
1PlatinumIBA
05/2013
1Platinum Compounds (Compounds, Platinum)IBA
05/2013
1Cisplatin (Platino)FDA LinkGeneric
05/2013

Therapy/Procedure

26Therapeutics
03/2019 - 11/2002
4Transplantation
03/2018 - 08/2005
3Drug Therapy (Chemotherapy)
09/2017 - 09/2010
1Lasers (Laser)
10/2014
1Injections
05/2013